What exactly are you looking for when it comes to columns? That’s an amazing question with multiple answers . The short answer though includes over the top grade, uniform, high density, low metal porous silica with a developed end capping for the finishing touch. The end result is that the columns can withstand the harshest of conditions while going ahead to deliver above and beyond expectations.
The fact that you can get it in many functional groups and particle sizes makes it surprisingly scalable and transferable to cover all bases with regards to your operations from R&D to QC. Particle sizes ranging from 1.6, 2.6 and 5um can do well to provide the necessary support to HPLC and UHPLC analytical systems. Different groups of R&D and QC can be interconnected courtesy of the different sizes available. What cutting edge columns do is make sure that time to tweak from one particle size to the next is reduced and the conditions are optimal. This can be attributed to the homogeneity of the silica gel, excellent perfomance, end capping and bonding of functional groups that keep the predictable consistency where columns are concerned.
By making the right decisions on column dimensions users can keep an optimal resolution while making shifts between particle sizes . This factor provides for easy transfer of methods between diverse particle sizes. In bid to make accurate calculations of the flow and gradient , chromatography software is used to give a determination. As one is using UPHLC during R&D and HPLC during quality control , the time used up to re-align analytical conditions in conjunction with optimal resolution is recovered.
When you are buying who you buy from with regard to company is important. If you have to buy its always advisable to get from companies that have been established for a long time. Those that are known to make columns from basic silica gel. Any company worth its salt will always regard you as a partner and will seek to listen to any issues you might raise and this are the go to companies. Those that are especially not afraid to get the customers first hand reaction to their product are a force to watch out for. The best of the best industries go ahead to use the information you give them to make top notch products for your consumption according to your preferences. These are just the ones you should go with . This information at hand what you want from the deal is one that serves your interest where the best pricing and the product they offer have exceeded your expectation in a positive way .